BISOHEART 5 mg 10 Tablets

Prescription status:

Prescription required

Manufacturer Name: MANKIND PHARMACEUTICALS LTD

Drug classification: Anti-Hypertensives - Selective Beta-blockers

What is this used for:

• Hypertension
• Angina pectoris
• Heart failure

When to not take this medicine:

• Hypersensitivity or allergy towards Bisoprolol
• Ischemic Heart disease
• Bronchospasm
• Sick sinus syndrome
• Pheochromocytoma
• Major surgery
• Diabetes
• Cardiogenic shock
• Peripheral vascular disease
• Calcium channel blockers

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

This medicine lowers the blood pressure by acting on the muscles of the heart to reduce the heart rate and increase the blood circulation

Side effects

• Dizziness (Less common)
• Bradycardia (Less common)
• Fatigue (Less common)
• Mild itching or rash (Less common)
• Confusion (Less common)
• Cold hands and feet (Less common)
• Diarrhea (Less common) 
• Shortness of breath (Less common)
• Lightheadedness (Less common)

Pregnancy warning:

Category C- Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative based on creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Aminophylline- Major

Inform your doctor about the use of either medicines. When these medicines are taken or used together, it may increase the effects of aminophylline. If you experience any signs and symptoms like insomnia, vomiting, nausea, arrhythmia, tremors, irregular heartbeat then inform to the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Clonidine- Major

Inform your doctor about the use of either medicines. When these medicines are taken or used together, it may cause very low blood pressure and slow heart rate. If you experience any signs and symptoms like dizziness, headache, arrhythmia, irregular heartbeat then inform to the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition

• Digoxin-Major

Inform your doctor about the use of either medicines. When these medicines are taken or used together, it may cause very low blood pressure and slow heart rate. If you experience any signs and symptoms like dizziness, headache, arrhythmia, irregular heartbeat then inform to the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition

• Diltiazem-Major

Inform your doctor about the use of either medicines. When these medicines are taken or used together, it may cause very low blood pressure and slow heart rate. If you experience any signs and symptoms like dizziness, headache, arrhythmia, irregular heartbeat then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition

• Alprazolam-Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together, it may cause very low blood pressure and slow heart rate. If you experience any signs and symptoms like dizziness, headache, arrhythmia, irregular heartbeat then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition

• Diclofenac-Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together regularly, it may reduce the effectiveness of this medicine. Inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition

Alcohol interactions:

Consumption of alcohol is not recommended while receiving/taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions:

N/A

Expert Advice:

1. These tablets are to be taken with food or immediately after food. Do not crush, chew, or break the tablet. Swallow it whole.
2. This medicine is to be taken at the same time of the day. Follow the missed dose instructions in case if you miss a dose.
3. Seek emergency medical help if you experience any of the side effects like Dizziness, Light-headedness, fainting, etc.
4. A sudden stoppage of this medicine may cause irregular heartbeat or blood pressure.
5. It is recommended to avoid driving or using heavy machinery immediately after consuming this medicine.

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost time for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

1. Store the medicine in a cool and dry place away from sunlight
2. Keep away from the reach of children
3. Discard the unused medicine safely after use

References:

1. Bisoprolol - DrugBank [Internet]. Drugbank.ca. 2020 [cited 12 August 2020]. Available from: https://www.drugbank.ca/drugs/DB00612

2. Bisoprolol Fumarate 5 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 12 August 2020]. Available from: https://www.medicines.org.uk/emc/product/3090/smpc

3. Bisoprolol: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 12 August 2020]. Available from: https://medlineplus.gov/druginfo/meds/a693024.html

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Keep away from direct sunlight

Store in a dry place