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Grapes (Angur): Uses, Benefits, Side Effects By Dr. Smita Barode

Introduction: 

Nothing feels more satisfying than tasting a batch of fresh grapes! These are not only important for curating a quality wine but are also used in refreshing fruit bowls and dishing out sinful desserts. It is because of this versatility, that grapes are also called as “Queen of fruits”. The scientific name of grapes is Vitis vinifera and it belongs to the family Vitaceae. Grapes are crunchy and juicy shots of heaven in various colours like black, green and red. They can be with or without seeds. About 8000 years ago, the cultivation of grapes began in the Middle East. They are now widely grown in Africa, Southern Europe, North and South America and Australia, India ranks among the top ten countries in the production of grapes. In India, 80% production is done in Maharashtra, Karnataka and Tamil Nadu. They are not only tasty but have several health benefits. Let us read about some evidence-based benefits which will tempt you to add grapes to your diet.1,2 

Did you know?

Nutritional Value of Grapes: 

Grapes are richly packed with various nutritional components that are given as follows:  

Nutritional components Value per 100 g 
Calories  107 kcal 
Carbohydrates  27 g 
Sugar 23 g 
Fibre 1.4 g 
Protein 1.1 g 
Total fat 0.2 g 
Potassium 288 mg 
Calcium 15 mg 
Sodium 3 mg 
Iron 0.5 mg 

Table 1: Nutritional value of grapes3 

Properties of Grapes (Angur): 

Including grapes in your diet might have a positive impact on retinal health. The antioxidants present in grapes may help protect and preserve the structure and function of the photoreceptors in the retina, promoting better vision and avoiding further damage.

Dr. Siddharth Gupta, B.A.M.S, M.D (Ayu)

Grapes show numerous scientifically proven properties and some of these properties are mentioned below:4 

Potential Uses of grapes for Overall Health: 

Did you know that adding grapes to your diet can be a secret weapon for youthful aging? These amazing fruits are packed with antioxidants that work their magic inside your cells, fighting off harmful oxidative stress and kickstarting the production of a powerful antioxidant called glutathione.

Dr. Rajeev Singh, BAMS

Some of the potential benefits of grapes are described as follows: 

1. Potential uses of grapes on cognitive function 

Studies support the association of grapes with an improvement in cognitive function. Grapes contain antioxidants like resveratrol which have anti-inflammatory and antioxidant properties which may help inhibit neurodegeneration. It also increases blood flow to the brain, and along with the presence of minerals like manganese, potassium and calcium, may improve brain health. Lee et al. conducted a study in 2017 to assess the effect of grape consumption on cognitive function. The study was conducted on ten participants with mild cognitive decline; this study showed a positive effect of grapes on cognitive function. Thus, grapes may have a positive impact on cognitive function. However, more studies are needed to support these claims.5 

2. Potential uses of grapes for liver disease 

Literature reviews suggest that grapes contain phytochemical resveratrol, which may have hepatoprotective effects against cholestatic, chemical and alcohol-mediated damage. Asim et al. conducted a study in 2022 to assess the effect of the consumption of grapes on non-alcoholic fatty liver disease in mice. This study showed that grapes helped modulate hepatic gene expression, preventing oxidative damage and ameliorating NAFLD. This indicates that the consumption of grapes may help manage NAFLD. Additionally, resveratrol may help reduce liver fibrosis and steatosis, which are features of chronic liver disease and thus, may exert a hepato-protective effect. However, scientific evidence to support these claims is limited, and we need more studies to support these claims.6,7 

3. Potential uses of grapes for managing lipid profile 

Polyphenol-rich food may have a favourable effect on lipid profile. Roberta et al. conducted a meta-analysis in 2020 to assess the impact of grapes on lipid profile. This meta-analysis showed that grapes’ consumption significantly reduced low-density lipoprotein (LDL) or bad cholesterol and increased high-density lipoprotein (HDL) or good cholesterol. This reduction in LDL cholesterol is attributed to the presence of polyphenols like resveratrol in grapes. Therefore, the consumption of grapes may help in reducing bad cholesterol and increasing good cholesterol. However, we need more scientific evidence to support these claims.8 

4. Potential uses of grapes for type II diabetes 

Type II diabetes mellitus is a global public health challenge affecting the majority of the population. It is characterized by an increased glucose production by the liver due to insulin resistance and beta-cell defects. Grapes have a low glycemic index, which may positively impact type II diabetes mellitus. Zunino et al. conducted a literature review in 2009 to assess the effect of grapes on type II diabetes. The review suggested that grapes may have the potential to reduce elevated blood glucose, improve beta cell function and protect against beta cell loss due to the presence of numerous polyphenols like resveratrol, catechins, anthocyanins, etc. The results of this study indicate that grapes may exert a positive impact on type II diabetes. Additionally, the presence of resveratrol may help in managing diabetic neuropathy. However, we need more research to support these claims.9 

5. Potential uses of grapes in cancer  

Several literature studies support the use of grapes as promising anticancer agents due to the presence of antioxidants. Zhou et al. conducted an in-vitro study in 2012 to assess the effect of grapefruit on small lung cancers. The results of this study supported the use of grapes for managing cancer. The anti-cancerous activity is attributed to the presence of antioxidants like proanthocyanidins which show inhibitory effects on several cancers.10 So, it might be possible that grapes can help in dealing with cancer. However, this finding needs further research to be applied practically. 

6. Other potential uses of grapes 

Though there are studies that show the benefits of grapes in various conditions, these are insufficient and there is a need for further studies to establish the true extent of the benefits of Grapes on human health.  

How to Use Grapes? 

You must consult a qualified doctor before including grapes in your diet. Do not discontinue or replace an ongoing treatment of modern medicine with grapes without consulting a qualified doctor.   

Side Effects of Grapes: 

Data regarding the side effects of grapes is limited and more research is required to verify the side effects of grapes on human health. However, if you experience any adverse reactions to grapes, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately for your symptoms. 

Precautions to take with Grapes: 

Eating grapes is okay if taken in moderate amounts. However, general precautions must be followed in the following conditions: 

Interactions with Other Drugs: 

Grapes (Angur) are known to interact with several drugs resulting in untoward effects. Drugs known to interact adversely with grapes are mentioned below; given with them are the conditions wherein they are advised. 

These interactions can result in unwanted effects on the body and may reduce the drug’s efficacy. However, you must always seek the advice of your Ayurvedic physician about the possible interaction of grapes with other drugs and follow the prescription thoroughly, as they will know your health condition and other medications you are taking.13 

Also Read: Glutathione Benefits: Exploring the Research-Based Health Advantages

Frequently Asked Questions: 

1) What is the scientific name of grapes? 

The scientific name of grapes is Vitis vinifera.1 

2) Which fruit is known as the “queen of fruits”?

Grapes are known as “queen of fruits”.1 

3)  Can grapes help in managing diabetes? 

Yes, grapes may help manage diabetes as they have a low glycemic index. However, more studies need to be done to support these claims in humans. Therefore, it is advised to consult a doctor for proper treatment.8 

4) Can grapes help in case of insomnia? 

The presence of melatonin in grapes may help manage insomnia. The scientific evidence supporting these claims is limited and therefore, it is advised to consult a doctor if you have any sleep-related issues.10  

5) What are the side effects of grapes consumption? 

Data regarding the side effect profile of grapes is limited, and more research is required to verify the side effects of grapes on human health. However, if you experience any adverse reactions to grapes, it is advised to discontinue its intake and immediately contact a doctor or your Ayurvedic physician who has prescribed it. They will be able to guide you appropriately considering your symptoms. 

References: 

  1. Grape. Available at: https://www.nhb.gov.in/Horticulture%20Crops/Grape/Grape1.htm (Accessed: November 29, 2022).  
  1. Parmar, R. (2022) 8 ways grapes can benefit your body, PharmEasy Blog. Available at: https://pharmeasy.in/blog/8-ways-grapes-can-benefit-your-body/ (Accessed: November 29, 2022).  
  1. Grapes, raw, red or green (European type, such as Thompson seedless) (no date) Grapes, raw, red or green (European type, such as Thompson seedless) nutrition facts and analysis. Available at: https://www.nutritionvalue.org/Grapes%2C_raw%2C_red_or_green_%28European_type%2C_such_as_Thompson_seedless%29_nutritional_value.html  (Accessed: November 29, 2022).  
  1. Pezzuto, John M et al. “Unraveling the relationship between grapes and health.” The Journal of nutrition vol. 139,9 (2009): 1783S-7S. doi:10.3945/jn.109.107458. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728694/ 
  1. Lee, Jooyeon et al. “Examining the impact of grape consumption on brain metabolism and cognitive function in patients with mild decline in cognition: A double-blinded placebo-controlled pilot study.” Experimental gerontology vol. 87, Pt A (2017): 121-128. doi:10.1016/j.exger.2016.10.004. Available at: https://pubmed.ncbi.nlm.nih.gov/27856335/ 
  1. Dave, Asim et al. “Consumption of Grapes Modulates Gene Expression, Reduces Non-Alcoholic Fatty Liver Disease, and Extends Longevity in Female C57BL/6J Mice Provided with a High-Fat Western-Pattern Diet.” Foods (Basel, Switzerland) vol. 11,13 1984. 5 Jul. 2022, doi:10.3390/foods11131984. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265568/ 
  1. Izzo, Carmine et al. “The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials.” Nutrients vol. 13,3 933. 13 Mar. 2021, doi:10.3390/nu13030933. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7999728
  1. Lupoli, Roberta et al. “Impact of Grape Products on Lipid Profile: A Meta-Analysis of Randomized Controlled Studies.” Journal of clinical medicine vol. 9,2 313. 22 Jan. 2020, doi:10.3390/jcm9020313. Available at: https://www.mdpi.com/2077-0383/9/2/313/htm 
  1. Zunino, Susanj. “Type 2 diabetes and glycemic response to grapes or grape products.” The Journal of nutrition vol. 139,9 (2009): 1794S-800S. doi:10.3945/jn.109.107631. Available at: https://academic.oup.com/jn/article/139/9/1794S/4670548 
  1. Zhou, Kequan, and Julian J Raffoul. “Potential anticancer properties of grape antioxidants.” Journal of oncology vol. 2012 (2012): 803294. doi:10.1155/2012/803294. Available at: https://pubmed.ncbi.nlm.nih.gov/22919383/ 
  1. Schneik4 (2021) 10 health benefits of grapes, Cleveland Clinic. Cleveland Clinic. Available at: https://health.clevelandclinic.org/health-benefits-of-grapes/ (Accessed: November 29, 2022).  
  1. Pal, D.A. (2022) Grape juice: Uses, benefits, side effects and more!, PharmEasy Blog. Available at: https://pharmeasy.in/blog/ayurveda-uses-benefits-side-effects-of-grape-juice/ (Accessed: November 29, 2022).  
  1. Grapefruit juice can affect how well some medicines work, U.S. Food and Drug Administration. FDA. Available at: https://www.fda.gov/consumers/consumer-updates/grapefruit-juice-and-some-drugs-dont-mix (Accessed: November 29, 2022).  

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

8 Ways Grapes Can Benefit Your Body

A sip of wine can lighten up your mood instantly!

Nothing feels as satisfying as tasting the first batch of authenticating wine from fresh grapes. The freshness of grapes is essential as it decides the taste of the wine. Not only wine but fresh grapes can be used in dishing out sinful desserts and refreshing the fruit bowls. There is no wonder that grapes are known as the ‘Queen of fruits’ because of their versatility.

Grapes are the small, crunchy shots of heaven. They are so juicy that they leave your taste buds up with their sweet flavour of goodness that you will be craving for more. They are unique in their taste, colour and texture. Grapes are available in various colours such as green, black and red with or without seeds. 

Grapes were first cultivated in the Middle East, 8000 years ago. Grapes are grown widely across the world including Southern Europe, Africa, Australia and North and South America.  

Grapes are not only tasty and pretty to look at but also have numerous essential health benefits. Various studies extensively found that grapes and their essential nutrients work for the well-being of the body. 

Nutritional fact of grapes 

 Grapes contain almost 80% of water and 20% of essential nutrients and vitamins. But that 20% of the nutrients are sufficient enough to provide our body with what it deserves. Grapes are rich in-

  1. Water
  2. Vitamins – vitamin C, vitamin K, vitamin A, vitamin B complex
  3. Minerals – potassium, copper, manganese
  4. Antioxidants – phytonutrients like carotenoids, polyphenols, lutein and zeaxanthin
  5. Dietary fibres

Health benefits of grapes

1: May help to prevent cancer:

Grapes are rich in antioxidants-polyphenols that help prevent certain types of cancer like stomach cancer. It also contains certain compounds such as catechins, resveratrol, anthocyanins and phenolic acids that may help in cancer prevention. Not only grapes, but their skin extract are helpful to induce cell cycle arrest and apoptosis in cancer cells. They help to kill free radicals and help reduce the infection. 

Some animal studies suggest that grape extract may help to cease the proliferation of cancer cells. However, human studies still need confirmation.

In Mexico, a different variety of grape is called the Muscadine grape. It has also been studied for its anti-cancer effects. They specifically help against prostate cancer as they contain ellagic acid and quercetin.

2: Help to manage blood sugar levels

Grapes are on a  little bit higher side of the sugar content that may make you wonder if they can be a choice for the people who have diabetes. Grapes have a low glycemic index. So you could add grapes to your anti-diabetic diet. Specifically, grape seeds are great at controlling high blood sugar levels.

3: Help to prevent diabetic complication:

Diabetic neuropathy and retinopathy are common complications of chronic diabetes. The resveratrol in grapes can help prevent diabetic neuropathy by boosting motor nerve conduction velocity and the nerve blood flow. 

Including grapes in the diet may increase the protective proteins in the retina. It helps to prevent diabetic retinopathy symptoms.

4: Good for the heart:

Grapes contain a compound called resveratrol that helps to reduce cholesterol absorption in the body. It leads to low levels of bad cholesterol. This benefit of grapes makes it essential to prevent cardiovascular diseases such as stroke, heart blockages, etc. 

5: Helps to maintain blood pressure:

Grapes are one of the best sources of potassium that helps in reducing sodium levels. Hence, they help to control high blood pressure. Grapes are also a good source of fibres which is important for maintaining a healthy cardiovascular system, including heart health and blood pressure. 

6: May boost brainpower:

Certain studies suggest that resveratrol present in grapes is helpful in increasing the blood supply to the brain. This compound helps in the growth and development of nervous tissue in the brain. It may help improve your memory and mood function in old age.

7: May improve bone health:

Grapes are rich in various minerals such as calcium, potassium, manganese and some vitamins. These nutrients are essential for healthy bone growth. A study atTexas University suggests that a daily intake of grapes can help get relief from knee pain, especially the pains triggered due to symptomatic osteoarthritis.

8: May protect against skin problems:

Grapes are well known for their effectiveness against skin problems. We usually see various face washes, face packs and cleansers that contain grape extract. The resveratrol in the grapes helps reduce the oxidative stress that heals your skin effectively from all the damages caused. This compound also protects the skin from UV-induced skin damage and may help prevent skin ageing and skin inflammation.

9: May improve sleep

If you are suffering from insomnia or have trouble staying asleep, grapes are the perfect low-calorie snack for you to munch on. Grapes contain a certain level of melatonin which regulates the sleep cycle and promotes uninterrupted sleep. 

10: Aids in effective age reversal

Grapes contain the potent antioxidant, Resveratrol which may protect cells and as a result affect the cell structure in the long run. It helps you stay youthful and regular consumption may increase your lifespan. 

11: May help maintain cholesterol levels

Grapes are a rich source of fibre that aids in lowering high cholesterol. The benefits of red grapes are endless. They are especially beneficial in carrying out the cholesterol from the bloodstream to the liver, the site where cholesterol is processed in the body. Consuming grapes in a certain quantity every day not only reduces LDL or ‘bad’ cholesterol but also the overall cholesterol levels of the body.

Grapes are available in various colours with different benefits. You can include them in your dietary routines in simple and easy ways. You can incorporate grapes into your diet whether fresh, frozen, as juice or wine.

Read more about: Exercise For High Blood Pressure: 5 Reasons It’s Important!

Disclaimer: The information provided here is for educational/awareness purposes only and is not intended to be a substitute for medical treatment by a healthcare professional and should not be relied upon to diagnose or treat any medical condition. The reader should consult a registered medical practitioner to determine the appropriateness of the information and before consuming any medication. PharmEasy does not provide any guarantee or warranty (express or implied) regarding the accuracy, adequacy, completeness, legality, reliability or usefulness of the information; and disclaims any liability arising thereof.

Links and product recommendations in the information provided here are advertisements of third-party products available on the website. PharmEasy does not make any representation on the accuracy or suitability of such products/services. Advertisements do not influence the editorial decisions or content. The information in this blog is subject to change without notice. The authors and administrators reserve the right to modify, add, or remove content without notification. It is your responsibility to review this disclaimer regularly for any changes.

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