Glisen VM 0.2 mg / 500 mg / 1 mg 10 Tablets

Best Price*116.53

MRP: 137.1Save ₹ 20.57

About

Prescription status:

Prescription required


Manufacturer Name: Alembic Ltd


Drug classification: Antidiabetic combinations


What is this used for:

  • Type 2 Diabetes


When to not take this medicine:

  • Hypersensitivity/Known Allergy to Metformin or Glimepiride or Voglibose
  • Liver disease
  • Kidney disease
  • Diabetic ketosis or diabetic coma or pre-coma.
  • Severe infection
  • Pre- Operative or Postoperative Conditions
  • Trauma
  • Gastrointestinal obstruction


How should I take the medicine?

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.


How this medicine works:

Glimepiride reduces the blood sugar levels by increasing the release of insulin from the pancreas. Metformin works by reducing the liver production of glucose. Voglibose works by lowering sugar levels in patients with type 2 diabetes by delaying the digestion and absorption of carbohydrates within the intestines.


Side effects

  • Anxiety (Less common)
  • Nausea and vomiting (Less common)
  • Depression (Less common)
  • Dizziness (Less common)
  • Irregular heartbeat (Less common)
  • Nightmares (Less common)
  • Seizures (Less common)
  • Diarrhoea (Rare)
  • Weakness or unusual tiredness (Less common)
  • Muscle cramps (Rare) 


Pregnancy warning: Category not assigned.

Use of this medicine is not recommended for individuals who are pregnant or planning to become pregnant unless absolutely necessary as the safety and efficacy of this medicine is not well established. Inform your doctor about the use of either medicines. All the risks and benefits should be discussed with the doctor before taking this medicine.


Lactation warning:

The use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.


Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.


Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.


Drug interactions:

  • Ranitidine- Moderate

Inform your doctor about the use of either medicines. When these medicines are taken together, it may lead to an increased concentration of metformin in the blood that may lead to an increased chance of occurrence of side effects like hypoglycemia, dizziness, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Aceclofenac- Major

Inform your doctor about the use of either medicines. When these medicines are taken together, it may lead to an increased concentration of glimepiride in blood that may lead to an increased chance of occurrence of side effects like hypoglycemia, dizziness, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Amiodarone- Major

Inform your doctor about the use of either medicines. When these medicines are taken together, it may lead to an increased concentration of metformin in the blood that may lead to an increased chance of occurrence of side effects like hypoglycemia, dizziness, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Captopril- Major

Inform your doctor about the use of either medicines. When these medicines are taken together, it may lead to an increased concentration of metformin in the blood that may lead to an increased risk of a serious and life-threatening condition called lactic acidosis. This is rare but happens when the patient is known to have liver or kidney dysfunction. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Acetazolamide-Major

Inform your doctor about the use of either medicines. When these medicines are taken together, there may be an increased risk of a serious and life-threatening condition called lactic acidosis. This is rare but happens when the patient is known to have liver or kidney dysfunction.  Sometimes, this can lead to heart failure or dehydration, etc. Inform your doctor on priority when you experience any unusual signs and symptoms like weakness, muscle ache, difficulty in breathing, chills, abdominal pain, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Gatifloxacin-Major

Inform your doctor about the use of either medicines. When these medicines are taken together it may affect the blood glucose levels. Hence, this medicine should not be used in the patient with diabetes. In severe cases of low blood glucose levels, it may lead to coma and sometimes death. Inform your doctor on priority when you experience any unusual signs and symptoms. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Ciprofloxacin-Moderate

Inform your doctor about the use of either medicines. When these medicines are taken together it may affect the blood glucose levels either low blood sugar levels or high in blood glucose levels. This may result in coma and sometimes death. This is especially noticed in elderly patients or patients known to kidney dysfunction. Inform your doctor on priority when you experience any unusual signs and symptoms like nausea, vomiting, weakness, irregular heartbeat, confusion, drowsiness, hunger, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

 

  • Clarithromycin-Moderate

Inform your doctor about the use of either medicines. When these medicines are taken together, this may result in a decrease in the blood sugar levels. Inform your doctor on priority when you experience any unusual signs and symptoms like confusion, tremors, nausea, weakness, hunger, irregular heartbeat, etc. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.


Alcohol interactions:

Consumption of alcohol is not recommended while taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.


Food interactions:

N/A


Expert Advice:

  1. This medicine can be taken with food. This will lower the chances of stomach complaints. 
  2. This medicine is not recommended to use in children below 18 years of age without your doctor’s advice.
  3. Lactic Acidosis- This medicine may cause Lactic acidosis i.e. formation of acid in the blood which may lead to death. If you notice any unusual signs then immediately report to your doctor.
  4. Care must be taken for the use of this medicine in individuals like Vitamin B12 deficiency, Stressful conditions like fever, surgery or accidents, etc.
  5. Seek emergency medical help if you experience any of the side effects like blistering or peeling of the skin, itching, swelling of the eyes, face, lip, mouth, difficulty in swallowing, hoarseness, rash on cheeks or arms, etc.
  6. It is recommended to check your blood glucose levels regularly.


Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.


Over dose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.


Storage Instructions:

Store the medicine in a cool and dry place. Keep the medicine away from the reach of the children


References:

1. [Internet]. Sanofi.in. 2020 [cited 11 September 2020]. Available from: https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Amaryl-MV-PI---Dec-2017.pdf?la=en

Customer Care

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Caution

Keep away from direct sunlight

Store in a dry place

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