HUMINSULIN 30 percent/70 Percent Penfill 3 ml

Prescription status:

Prescription required

Manufacturer Name: Eli Lilly And Company (India) Pvt Ltd

Drug classification: 

Synthetic insulins, Regular Insulin and Intermediate Insulin combinations

What is this used for:

• Type-1 Diabetes
• Type -2 Diabetes

When to not take this medicine:

• Hypersensitivity
• Heart failure, low blood levels of potassium
• Liver or kidney disease
• Pregnant or going to be pregnant

How should i take the medicine:

Take this medicine as strictly directed by the doctor

How this medicine works:

It works by replacing the insulin that is normally produced by the body and by helping move sugar from the blood into other body tissues

Side effects

• Fever (common)
• Cough (common)
• Sore throat (common)
• Allergic reactions (Less common)
• Wheezing (less common)
• Difficulty breathing or swallowing (rare)
• fast pulse (rare)
• Sweating (common)
• Weakness (less common)
• Muscle cramps (rare)

Pregnancy warning: Category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Aspirin - Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together may increase the risk of hypoglycemia, or low blood sugar.If you experience any signs and symptoms like dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Sitagliptin - Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together it may help control blood glucose levels, which may lead to a reduction in your dosage requirement of insulin or any other diabetic medications you are receiving. If you experience any signs and symptoms like dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Metformin - Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together can increase the risk of hypoglycemia, or low blood sugar. If you experience any signs and symptoms like dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Omega-3 polyunsaturated fatty acids - Unknown

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient.

• Ciprofloxacin - Major

Inform your doctor about the use of either medicines. When these medicines are taken or used together can sometimes affect blood glucose levels. If you experience any signs and symptoms like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Clobetasol topical - Minor

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient.

Alcohol interactions:

Consumption of alcohol is not recommended while receiving/taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions: N/A

Expert Advice:

1. Food instruction (before food or with food or after food) (with or without food) 
2. Do not inject insulin into a vein or a muscle.
3. Insulin requirements may vary in individuals who experience conditions like hypothyroidism, trauma, infection, surgery, hyperthyroidism, etc.
4. Do not inject this medicine into skin that is damaged, tender, bruised, pitted, thickened, scaly, or has a scar or hard lump.
5. Report any side effects like nausea, vomiting, etc.experienced immediately to the doctor.

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

• Refrigerate and use until expiration date
• Store at room temperature and use within 28 days.
• Keep away from children

References:

1. [Internet]. Accessdata.fda.gov. 2020 [cited 28 October 2020]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018780s120lbl.pdf

2. NPH Insulin [Internet]. Ncbi.nlm.nih.gov. 2020 [cited 28 October 2020]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK549860/

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Keep away from direct sunlight

Store in a dry place