IVEPRED 16 mg 10 Tablet

Prescription status:

Prescription required

Manufacturer Name: 

Sun Pharmaceutical Industries Ltd

Drug classification: 

Glucocorticoids

What is this used for:

This medicine is used for the treatment of a wide range of diseases of the organ systems like

• Endocrine disorders - Primary and secondary adrenal insufficiency, Congenital adrenal hyperplasia
• Rheumatic disorders- Rheumatoid arthritis, Juvenile chronic arthritis, Ankylosing spondylitis
• Collagen diseases/arteritis- Systemic lupus erythematosus, Systemic dermatomyositis (polymyositis), Rheumatic fever with severe carditis, Giant cell arteritis/polymyalgia rheumatica
• Dermatological diseases - Pemphigus Vulgaris
• Allergic states- Severe seasonal and perennial allergic rhinitis, Drug hypersensitivity reactions, Serum sickness, Allergic contact dermatitis, Bronchial asthma
• Ophthalmic diseases- Anterior uveitis (iritis, iridocyclitis), Posterior uveitis, Optic neuritis
• Respiratory diseases- Pulmonary sarcoid, Fulminating or disseminated tuberculosis (with appropriate anti-tuberculous chemotherapy), Aspiration of gastric contents
• Haematological disorders - Idiopathic thrombocytopenic purpura, Haemolytic anaemia (autoimmune)
• Neoplastic diseases- Leukaemia (acute and lymphatic), Malignant lymphoma
• Gastro-intestinal diseases- Ulcerative colitis, Crohn's disease
• Miscellaneous- Tuberculous meningitis (with appropriate anti-tuberculous chemotherapy), Organ Transplantation

When to not take this medicine:

• Hypersensitivity or allergy towards this medicine or ingredients present along with it
• Systemic fungal infections
• Live or live, attenuated vaccines in individuals with current history 

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

This medicine works by binding to and activating certain genes within the cells that control inflammation and cellular processes like metabolism, immunity, protein synthesis, etc.

Side effects:

• Leukocytosis (Unknown)
• Hypopituitarism (Unknown)
• Sodium retention (Unknown)
• Fluid retention (Unknown)
• Cardiac failure congestive (in susceptible patients) (Unknown)
• Myocardial rupture following myocardial infarction (Unknown)
• Pulmonary embolism (Unknown)
• Hiccups (Unknown)
• Skin atrophy (Unknown)
• Acne (Unknown)
• Muscular weakness(Unknown)
• Irregular Menstruation (Unknown)
• Slow or Impaired Healing (Unknown)

Pregnancy warning: Category C

There are no adequate and well-controlled studies in pregnant women. Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• BCG Vaccine - Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

• Clarithromycin - Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

• Ergotamine - Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

• Hepatitic A/B/C Vaccine- Major

Inform your doctor about the use of either medicines. The use of these medicines is contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

• Silodosin - Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

• Aceclofenac - Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient. 

Alcohol interactions:

Consumption of alcohol is not recommended while receiving/taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions: N/A.

Expert Advice:

1. Report any side effects like nausea, vomiting, etc.experienced immediately to the doctor.
2. This medicine should not be given to children and adolescents under 18 years old.
3. Do not drive or operate machinery if you feel dizzy or drowsy while taking this medicine

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

• Keep this medicine out of the sight and reach of children. 
• Do not throw away any medicines via wastewater or household waste

References:

1. Medrone 16mg Tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 29 October 2020]. Available from: https://www.medicines.org.uk/emc/product/1086/smpc#PHARMACOLOGICAL_PROPS

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For Queries/ Feedback/Complaints, Contact our customer care Executive at: Phone:1860-1234-1234, Email-support@medlife.com

Keep away from direct sunlight

Store in a dry place