LITHOSUN SR 400 mg 10 Tablet

Prescription status:

Prescription required

Manufacturer Name:

Sun Pharmaceutical Industries Ltd

Drug classification:

Antimaniac agent

What is this used for:

• Moderate to Severe Mania
• Bipolar Disorder

When to not take this medicine:

• Hypersensitivity/Known Allergy to this medicine or ingredients present along with it
• Dementia
• Blood cell deficiency (Neutropenia)
• Hypotension(low blood pressure)
• Liver damage or liver disease
• Severe Kidney Damage or Kidney Failure
• Seizure disorder

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

This medicine helps in the treatment of extreme levels of mood and enthusiasm.

Side effects

• Dizziness (unknown)
• Drowsiness (Less common)
• Suicidal thoughts (Common)
• Mood changes (Common)
• Insomnia (common)
• Anorexia (Loss of appetite) (Common)
• Diarrhea (Less common)
• Abdominal Pain (Less common)
• Vomiting( Less common)
• Nightmares (Less common)
• Headache (unknown)
• Body pain (unknown)

Pregnancy warning: Use of this medicine is not recommended for individuals who are pregnant or planning to become pregnant unless absolutely necessary as the safety and efficacy of this medicine is not well established. Inform your doctor about the use of either medicines. All the risks and benefits should be discussed with the doctor before taking this medicine.

Lactation warning:

The use of this medicine is not recommended for lactating and breastfeeding mothers unless necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative based on creatinine clearance values

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Certinib-Major

Inform your doctor about the use of either medicine. When these medicines are taken together, ithough it is a rare side effect, t may result in elevated risk of abnormal heart rhythm which may lead to serious or highly life threatening. If you experience any unsual signs and symptoms like fainting, lightheadedness, shortness of breath, irregular heart rhythms etc. It is important to inform your doctor about the use of these medications before taking this medicine. Appropriate dose adjustments or suitable alternatives may be considered based on clinical condition.

• Clozapine-Major

Inform your doctor about the use of either medicine. When these medicines are taken together, ithough it is a rare side effect, t may result in elevated risk of abnormal heart rhythm which may lead to serious or highly life threatening. If you experience any unsual signs and symptoms like fainting, lightheadedness, shortness of breath, irregular heart rhythms etc. It is important to inform your doctor about the use of these medications before taking this medicine. Appropriate dose adjustments or suitable alternatives may be considered based on clinical condition.

• Diclofenac-Major

Inform your doctor about the use of either medicine. When these medicines are taken together, the levels of lithium may be increased and may cause toxicity. Patients with known history of kidney or liver or heart problem are more susceptible.  It is important to inform your doctor about the use of these medications before taking this medicine. Appropriate dose adjustments or suitable alternatives may be considered based on clinical condition.

• Duloxetine-Major

Inform your doctor about the use of either medicines. When these medicines are taken together, may increase the risk of syndrome called serotonin syndrome. This may have signs and symptoms like changes in blood pressure, tremors, abnormal heart rate, confusion, seizures, blurred vision etc. In severe cases sometimes may lead to coma or death. It is important to inform your doctor about the use of these medications before taking this medicine. Appropriate dose adjustments or suitable alternatives may be considered based on clinical condition.

Alcohol interactions:

Consumption of alcohol is not recommended while taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions: N/A

Expert Advice:

1. This medicine can be taken with or without food. Do not chew or crush the tablet. Take it as a whole.
2. Care must be taken in individuals with conditions like Diabetes, Bleeding disorders, Bone and joint diseases like osteoporosis, arthritis, etc.
3. Avoid driving or use of heavy machinery as the use of this medicine may cause drowsiness, loss of concentration, and dizziness.
4. It is recommended to monitor the functioning of liver, kidneys and thyroid while taking this medicine.
5. Inform any side effects experienced immediately to the doctor.

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost time for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose. 

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

1. Store this medicine in a cool and dry place away from moisture. 
2. Keep the medicine away from the reach of children

References:

1. Lithium - DrugBank [Internet]. Drugbank.ca. 2020 [cited 8 December 2020]. Available from: https://www.drugbank.ca/drugs/DB01356
2. Drugs H. Lithium: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 8 December 2020]. Available from: https://medlineplus.gov/druginfo/meds/a681039.html

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Keep away from direct sunlight

Store in a dry place