Lopamide 2 mg 10 Tablets

Prescription status:

Prescription required

Manufacturer Name: 

Torrent Pharmaceuticals Ltd

Drug classification: 

Anti-Diarrheal Agents

What is this used for:

• Acute Diarrhea
• Irritable bowel syndrome

When to not take this medicine:

• Hypersensitivity/Known Allergy to this medicine
• Cardiac Arrhythmias
• Liver disease
• Kidney disease

How should I take the medicine?

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

This medicine increases the bowel movement time by binding to the intestinal receptors.

Side effects 

• Constipation (Uncommon)
• Nausea (Uncommon)
• Flatulence (Uncommon)
• Abdominal pain (Rare)
• Abdominal discomfort (Rare) 
• Dry mouth (Rare) 
• Upper Abdominal pain (Rare) 
• Vomiting (Rare)
• Dyspepsia (Rare)
• Angioedema (Rare)
• Fatigue (Rare)

Pregnancy warning: Category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Ritonavir- Moderate 

Inform your doctor about the use of either medicine. When these medicines are taken together there may be an increased risk of developing side effects. If you experience any unusual symptoms like nausea, dizziness, headache, weakness, etc. Inform your doctor on priority. Appropriate dose adjustments or suitable alternative may be considered based on your condition

• Desmopressin-Major

Inform your doctor about the use of either medicine. When these medicines are taken together there may be an increased risk of developing side effects. If you experience any unusual symptoms like nausea, dizziness, headache, weakness, etc. Inform your doctor on priority. Appropriate dose adjustments or suitable alternative may be considered based on your condition

• Itracoazole- Major

Inform your doctor about the use of either medicine. When these medicines are taken together there may be an increased risk of developing side effects. If you experience any unusual symptoms like nausea, dizziness, headache, weakness, etc. Inform your doctor on priority. Appropriate dose adjustments or suitable alternative may be considered based on your condition.

• Gemfibrozil- Major

Inform your doctor about the use of either medicine. When these medicines are taken together there may be an increased risk of developing side effects. If you experience any unusual symptoms like nausea, dizziness, headache, weakness, etc. Inform your doctor on priority. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

• Chlorpromazine- Moderate

Inform your doctor about the use of either medicine. When these medicines are taken together there may be an increased risk of developing side effects. If you experience any unusual symptoms like nausea, dizziness, headache, weakness, etc. Inform your doctor on priority. Appropriate dose adjustments or suitable alternatives may be considered based on your condition.

Alcohol interactions:

Consumption of alcohol is not recommended while taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions:

N/A

Expert Advice:

1. This medicine is not recommended for children below 2 years of age unless prescribed by the doctor with suitable dose adjustments.
2. Care must be taken for individuals with cardiovascular disorders as use of this medicine may cause irregular heart rhythms.
3. Discuss with the doctor about the risk associated with this medicine if taken during pregnancy or breastfeeding.

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

Store the medicine in a cool and dry place. Keep the medicine away from the reach of the children

References:

1. Imodium 1 mg/5 ml oral solution - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 19 October 2020]. Available from: https://www.medicines.org.uk/emc/product/188/smpc#PHARMACOLOGICAL_PROPS

2. [Internet]. Accessdata.fda.gov. 2020 [cited 19 October 2020]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017694s052lbl.pdf

3. Loperamide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 19 October 2020]. Available from: https://medlineplus.gov/druginfo/meds/a682280.html

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Keep away from direct sunlight

Store in a dry place