Pbren M 75 mg/750 mcg 10 Capsules

Prescription status:

Prescription required

Manufacturer Name:

La Renon Healthcare Pvt Ltd

Drug classification:

GABA precursors + Vitamin B combinations 

What is this used for:

• Peripheral Neuropathic Pain

When to not take this medicine:

• Hypersensitivity or allergy towards this medicine

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

Pregabalin binds to the auxiliary subunit of voltage-gated calcium-channels in the central nervous system.Methylcobalamin is one of the form of vitamin B and plays a role as co factors in various enzyme synthesis and metabolism processes.

Side effects

• Angioedema (Unknown)
• Fatigue (Unknown)
• Sleepiness (Unknown)
• Flushing (Unknown)
• Headache (Unknown)
• Nausea (Unknown)
• Dizziness (Unknown)
• Visual Disturbances(Unknown)
• Ankle swelling (Unknown)
• Abdominal pain (Unknown)

Pregnancy warning:

Unknown - Use of this medicine is not recommended if you are pregnant or planning to become pregnant unless necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative based on creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Gabapentin- Major

Inform your doctor about the use of either medicines. When these medicines are taken together combination it may decrease the levels of this medicine in blood and may cause side effects like slow pulse, loss of appetite, nausea, visual changes, or irregular heartbeats. Appropriate dose adjustments or suitable alternate medicine may be considered based on the condition.

•  Oxycodone- Major

Inform your doctor about the use of either medicines. When these medicines are taken together combination it may decrease the levels of this medicine in blood and may cause side effects like slow pulse, loss of appetite, nausea, visual changes, or irregular heartbeats. Appropriate dose adjustments or suitable alternate medicine may be considered based on the condition.

• Phenytoin- Major

Inform your doctor about the use of either medicines. When these medicines are taken together combination it may increase the levels of this medicine in blood and may cause side effects like slow pulse, loss of appetite, nausea, visual changes, or irregular heartbeats. Appropriate dose adjustments or suitable alternate medicine may be considered based on the condition.

•  Clonazepam - Moderate

Inform your doctor about the use of either medicines. When these medicines are taken together combination it may increase the levels of this medicine in blood and may cause side effects like slow pulse, loss of appetite, nausea, visual changes, or irregular heartbeats. Appropriate dose adjustments or suitable alternate medicine may be considered based on the condition.

• Amitriptyline - Moderate

Inform your doctor about the use of either medicines. When these medicines are taken together combination it may increase the levels of this medicine in blood and may cause side effects like slow pulse, loss of appetite, nausea, visual changes, or irregular heartbeats. Appropriate dose adjustments or suitable alternate medicine may be considered based on the condition.

Alcohol interactions:

Consumption of alcohol is not recommended while receiving/taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions:

N/A

Expert Advice:

1. These tablets can be taken, with or without food. Do not crush, chew, or break the tablet. Swallow it whole.
2. Seek emergency medical help if you experience any of the side effects like Dizziness, Light-headedness, fainting, etc.
3. Sudden stoppage of this medicine may cause symptoms of withdrawal like insomnia, headache, nausea, anxiety, diarrhoea, flu syndrome, nervousness, depression, pain, convulsion, hyperhidrosis and dizziness
4. It is recommended to avoid driving or using heavy machinery immediately after consuming this medicine.

Missed dose instructions:

Take this medicine as soon as you remember. However, if it is almost time for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Overdose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

1. Store the medicine in a cool and dry place away from sunlight
2. Keep away from the reach of children
3. Discard the unused medicine safely after use

References:

1. NOVA M Capsules [Internet]. CiplaMed. 2020 [cited 23 September 2020]. Available from: https://www.ciplamed.com/content/nova-m-capsules

2. Neurica-M 75 Full Prescribing Information, Dosage & Side Effects | MIMS Myanmar [Internet]. Mims.com. 2020 [cited 23 September 2020]. Available from: https://www.mims.com/myanmar/drug/info/neurica-m%2075?type=full

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Keep away from direct sunlight

Store in a dry place