SEPTRAN DS 800 mg/160 mg 10 Tablet

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Pack size
10Tablet

About

Prescription status:

Prescription required 

 

Manufacturer Name: Glaxosmithkline Pharmaceuticals Ltd

 

Drug classification: sulfonamides, antibiotics

 

What is this used for:

  • Urinary tract infections, 
  • Acute otitis media in pediatric patients (when clinically indicated), 
  • Acute exacerbations of chronic bronchitis in adults, 
  • Enteritis caused by susceptible Shigella, 
  • Prophylaxis and treatment of Pneumocystis jiroveci pneumonia, 
  • Travelers' diarrhea

 

 When to not take this medicine:

  • Hypersensitivity or Allergy towards Sulfamethoxazole or Trimethoprim
  • Liver diseases
  • Kidney disease
  • Patients with a history of drug-induced immune thrombocytopenia 
  • Acute porphyria.
  • Infants during the first 6 weeks of life.

 

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

 

How this medicine works:

This medicine works by preventing the bacteria from producing folic acid, a nutrient required for bacterial multiplication. 

 

Side effects

  • Abdominal or stomach pain (Less common)
  • Blood in the urine or stools (Less common)
  • Feeling of discomfort (Less common)
  • Headache (Less common)
  • Nausea (Common)
  • Vomiting (Common)
  • Skin rash (Common)
  • Allergic reaction (Common)

 

Pregnancy warning: 

(Not assigned)/ unknown : Use of this medicine is not recommended for individuals who are pregnant or planning to become pregnant unless absolutely necessary as the safety and efficacy of this medicine is not well established. Inform your doctor about the use of either medicines. All the risks and benefits should be discussed with the doctor before taking this medicine.

 

Lactation warning:

Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

 

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.

 

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

 

Drug interactions:.

 

  • BCG vaccine-Moderate

Inform your doctor about the use of either medicine. When these medicines are taken together it The therapeutic efficacy of BCG vaccine can be decreased. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

 

  • Gentamicin-Moderate

Inform your doctor about the use of either medicine. When these medicines are taken together Gentamicin may decrease the excretion rate of this medicine. It may lead to several undesirable effects. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

 

  • Typhoid vaccine-Moderate

Inform your doctor about the use of either medicine. When these medicines are taken together The therapeutic efficacy of Typhoid vaccine can be decreased. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

 

  • Cholera vaccine-Moderate

Inform your doctor about the use of either medicine. When these medicines are taken together it decreases the therapeutic efficacy of Cholera vaccine. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

 

Alcohol interactions:

Consumption of alcohol is not recommended while receiving this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

 

Food interactions:

N/A.

 

Expert Advice: 

  • This medicine can be taken with or without food.  
  • Atrophic gastritis has been noted with long-term use of this medicine.
  • Seek immediate medical care if you experience any unusual side effects such as Muscle twitching, Coughing up blood, General body swelling, Paralysis

 

 

Missed dose instructions: 

Take this medicine as soon as you remember. However if it is almost the time for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

 

Over dose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

 

Storage Instructions:

  • Store in a cool and dry place.
  • Keep away from the reach of children

 

References:

1.Co-Trimoxazole 16 mg/ 80mg per ml for Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 21 December 2020]. Available from: https://www.medicines.org.uk/emc/product/4669/smpc#CONTRAINDICATIONS

2. Sulfamethoxazole | DrugBank Online [Internet]. Go.drugbank.com. 2020 [cited 21 December 2020]. Available from: https://go.drugbank.com/drugs/DB01015


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Caution

Keep away from direct sunlight

Store in a dry place

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