ZYTANIX 5 mg 10 Tablet

Prescription status:

Prescription required

Manufacturer Name: 

ZYDUS CADILA

Drug classification: 

Diuretics 

What is this used for:

• Hypertension
• Edema

When to not take this medicine:

• Hypersensitivity
• If you suffer from heart rhythm problems, diabetes, gout, or kidney, liver, thyroid, or parathyroid disease.
• During pregnancy

How should i take the medicine:

Take this medicine with an adequate amount of water as directed by the physician. Do not take this medicine in small or larger amounts than recommended.

How this medicine works:

This medicine works by making the kidneys get rid of unneeded water and salt from the body into urine

Side effects:

 Common: 

• Upset stomach
• Drowsiness

Less Common:

• Muscle cramps
• Dizziness
• Confusion
• Thirst

Rare:

• Vomiting
• Stomach cramps
• Decreased sexual ability
• Blurred vision
• Rapid, excessive weight loss
• Severe skin rash with itching
• Difficulty breathing or swallowing 

Pregnancy warning: Category B

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Lactation warning: 

Use of this medicine is not recommended for lactating and breastfeeding mothers unless absolutely necessary. Inform your doctor about the use of this medicine. All the risks and benefits should be discussed with the doctor before taking this medicine.

Renal dose adjustments:

Care must be taken for individuals with kidney disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative on the basis of creatinine clearance values.

Hepatic dose adjustments:

Care must be taken for individuals with liver disease while taking this medicine. Please discuss appropriate dose adjustments with your doctor. Your doctor may also prescribe a suitable alternative.

Drug interactions:

• Amantadine- Minor

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient.

• Amifostine- Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together may have additive effects in lowering your blood pressure. If you experience any signs and symptoms like headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Aminolevulinic acid- Major

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient.

• Benazepril- Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together may be additive in lowering your blood pressure. If you experience any signs and symptoms like dizziness, fainting, or headaches then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Calcitriol- Moderate

Inform your doctor about the use of either medicines. When these medicines are taken or used together, can cause your blood calcium levels to become too high.If you experience any signs and symptoms like dizziness, drowsiness, weakness, lethargy then inform the doctor on priority. Appropriate dose adjustments may be done, or suitable alternate medicine may be considered based on the condition.

• Dicumarol- Minor

Inform your doctor about the use of either medicines. The use of these medicines are contraindicated since they may give serious adverse reactions which may lead to coma or death. Suitable alternatives may be considered based on the condition of the patient.

Alcohol interactions:

Consumption of alcohol is not recommended while receiving/taking this medicine as it may cause interactions and lead to serious adverse effects and may worsen the health condition.

Food interactions: N/A.

Expert Advice:

1. Do not take this very late otherwise you may have to wake up to go to the toilet.
2. Report any side effects like nausea, vomiting, etc.experienced immediately to the doctor.
3. Do not drive a car or operate machinery until you know how this drug affects you.

Missed dose instructions:

Take this medicine as soon as you remember. However if it is almost the for your next dose skip the dose and go back to your regular dosing schedule. Do not double dose to make up for the missed dose.

Over dose Instructions:

Seek emergency treatment or contact your physician in case if you experience any unusual signs and symptoms during the treatment with this medicine.

Storage Instructions:

• Keep this medicine in the container it came in, tightly closed, and out of reach of children. 
• Store it at room temperature and away from excess heat and moisture (not in the bathroom).

References:

1. Drugs H. Metolazone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 7 December 2020]. Available from: https://medlineplus.gov/druginfo/meds/a682345.html#:~:text=Metolazone%2C%20is%20used%20to%20reduce,diuretics%20('water%20pills').
2. DailyMed - LISINOPRIL tablet [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 7 December 2020]. Available from: https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=7d6c31e2-b5a4-4279-8013-a8dad37ea73b#:~:text=1.1%20Hypertension-,Lisinopril%20tablet%20USP%20is%20indicated%20for%20the%20treatment%20of%20hypertension,primarily%20strokes%20and%20myocardial%20infarctions.

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Keep away from direct sunlight

Store in a dry place